Explore Research Innovation at the David Geffen School of Medicine
Current physical exams and tests, such as of blood and urine, don’t tell physicians anything significant about the health of a person’s immune system — even though a rampant and chronic immune response might be destroying joints, tissue, and organs or that a weak, ineffectual immune system is permitting recurrent infections to flourish or cancer to grow.
This needs more fleshing out, but ideally would be a 'What if' type paragraph on what's possible. What if during a wellness check-up, your primary care physician offers you two new exams in addition to listening to your heart, checking your blood pressure and cholesterol levels, and other standard tests. These tests could give you an in-depth look at your own blood-based immune system and gut microbiome. You'd leave the doctor’s office not only with a statin prescription for your cholesterol, but also a cocktail of immune system boosters tailored to you, as well as a script for gut biota.
UCLA scientists say this vision highlights a new understanding about human health — that the immune system is a player in, if not the cause of, many human diseases and, possibly, aging.
Dr. Esrailian and his Division colleagues are working to understand how the microbiome and the immune system interact to cause chronic digestive diseases such as IBD and IBS using cutting-edge scientific approaches.
Dr. Donald Kohn, M.D., studies the basic biology of blood stem cells in order to develop strategies to isolate, genetically modify, and re-transplant them back into people. He has translated his research and developed a life-saving stem cell gene therapy for “bubble baby” disease, a genetic immune deficiency disorder.
Dr. Lo is a physician-scientist working to advance the understanding of immune mechanisms that determine response and resistance to two of the most promising therapies for advanced melanoma, the deadliest form of skin cancer.
Placeholder text here, as we need another impactful researcher and a description of the work to go in this spot on the website. We could only have three here, but I'm sure there are others to highlight, it is just a matter of elevating the correct folks to this page.