Explore Research Innovation at the David Geffen School of Medicine
Current physical exams and tests, such as of blood and urine, don’t tell physicians anything significant about the health of a person’s immune system — even though a rampant and chronic immune response might be destroying joints, tissue, and organs or that a weak, ineffectual immune system is permitting recurrent infections to flourish or cancer to grow.
This needs more fleshing out, but ideally would be a 'What if' type paragraph on what's possible. What if during a wellness check-up, your primary care physician offers you two new exams in addition to listening to your heart, checking your blood pressure and cholesterol levels, and other standard tests. These tests could give you an in-depth look at your own blood-based immune system and gut microbiome. You'd leave the doctor’s office not only with a statin prescription for your cholesterol, but also a cocktail of immune system boosters tailored to you, as well as a script for gut biota.
UCLA scientists say this vision highlights a new understanding about human health — that the immune system is a player in, if not the cause of, many human diseases and, possibly, aging.
Placeholder Text: Antoni Ribas, M.D., Ph.D. is Professor of Medicine, Professor of Surgery, and Professor of Molecular and Medical Pharmacology at the University of California Los Angeles (UCLA), Director of the Tumor Immunology Program at the Jonsson Comprehensive Cancer Center (JCCC) and the Chair of the Melanoma Committee at SWOG.
Dr. Donald Kohn, M.D., studies the basic biology of blood stem cells in order to develop strategies to isolate, genetically modify, and re-transplant them back into people. He has translated his research and developed a life-saving stem cell gene therapy for “bubble baby” disease, a genetic immune deficiency disorder.
Placeholder Text: Gay M. Crooks is the Rebecca Smith Professor in the Department of Pathology & Laboratory Medicine and Professor of Pediatrics in the David Geffen School of Medicine, UCLA.
Placeholder Text: Dr. Manish Butte is Associate Professor of Pediatrics at the David Geffen School of Medicine at UCLA. He serves as Chief of the Division of Allergy, Immunology and Rheumatology.