Explore Research Innovation at the David Geffen School of Medicine
Essential to good health, the inflammatory response protects people from infection and other damage. However, improperly regulated, long-term inflammation can lead to disease.
Inflammatory processes involve an intricate array of triggers, molecules, and processes. Although we learn new and surprising things about inflammation every day, many of its processes remain mysterious.
UCLA Immunity, Inflammation, Infection, & Transplantation (I3T) scientists believe we can achieve optimal outcomes in a range of diseases by understanding and controlling inflammation.
What if we could understand and regulate inflammation?
What if we demystified the enigmatic processes of inflammation? We could advance patient care by defining the molecular pathways driving a range of inflammatory responses, from those that work as nature intended to those that linger and lead to disease. Using a map of these processes, physicians could turn inflammation up or down to achieve balance and help patients heal.
I3T scientists bring us closer to inflammatory homeostasis by elucidating inflammation’s activation cascade, relationship to metabolism, role in cancer, and more.
Placeholder Text: Dr. Christina Charles has participated in a variety of clinical trials aiming to develop novel therapies for rheumatoid arthritis.
Dr. Genhong Cheng believes we can learn how to heal patients by studying the undisputed experts of disease defense: immune system cells. He follows the independent processes of innate and adaptive immunity, and he also investigates how and why the two systems sometimes work together.
Placeholder Text: Dr. Stephen T. Smale strives to understand gene expression during inflammatory and innate immune responses.
Dr. Steven Bensinger and his team opened a new line of immunological inquiry by substantiating links between the immune system and the metabolism—two systems previously believed to perform disparate functions in the pursuit of distinct biological goals.