The UCLA Cardiovascular Research Theme will provide cardiac muscle cells as a core service at a highly subsidized rate. The goal of this service is to provide a readily available resource of cardiac muscle cells for investigators performing ex vivo experiments on cardiac muscle cells.
Two types of cardiac muscle cells will be provided.
- Neonatal rat ventricular cardiomyocytes (NRVM). These cells beat in the dish for 3-7 days and provide a platform for determining effects of toxins, drugs or other genetic manipulation of the cardiac muscle cell.
- Human embryonic stem cell or human iPSC derived cardiomyocytes. H9 or other NIH approved lines and UCLA approved lines are used as a source for the differentiation of cardiac muscle cells. Human pluripotent stem cell derived cardiac muscle cells will be handed to investigators at their preferred time point of differentiation. To maintain consistency, standard differentiation programs are used. Crispr/Cas edited hPSC derived cardiomyocytes will be introduced as a core service in the recent future.
To place orders for NRVM or hPSC derived cardiac muscle, please write to Arjun Deb, MD, Director, UCLA Cardiovascular Research Theme at firstname.lastname@example.org.