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Human Genetics

Department of Human Genetics

Human Genetics
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Department of Human Genetics

Why Innovation Lives Here

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Collaboration is a Short Walk Away

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Walk to a range of innovation hubs in less than 5 minutes. UCLA’s compact, walkable campus enables experts across disciplines to share facilities, equipment, and most importantly, conversations that lead to synergistic discoveries.

Innovation Lives Here

It's a 5 minute or less walk from our location to any of the following innovation centers on campus. Your next collaboration is right down the street.


Terasaki Life Sciences Building

California Nanosystems Institute

Biomedical Sciences Research Building

Henry Samueli School of Engineering

Neuroscience Research Building

Collaboration is a short walk away

When You're Not Walking

UCLA without a car

Photo/Daily Bruin

Nearly 75,000 employees and students commute to UCLA on a regular basis.

UCLA Transportation strives to provide smart and sustainable commute options for students, staff and faculty by offering discounted public transit passes, bicycle incentive programs, vanpool programs, carpool parking discounts and more. By embracing a low-car or car-free lifestyle, staff and faculty support UCLA's efforts to create a vibrant, sustainable and healthy campus.

Whether you are on campus or in the surrounding Westwood area, there is plenty to do and explore.

No car on campus, no problem

Faculty Research Interests

Our accomplished faculty members collaborate on a wide spectrum of research interests covering everything from the genetic basis of complex traits to computational methods for understanding genetic risk factors for common diseases.  

Faculty Member Research Interest
Valerie Arboleda, MD PhD The overarching research goals in the lab is to integrate large-scale data sets to improve our biological understanding and clinical treatment of human disease.
Paul Boutros, PhD Personalizing therapy for cancer by developing novel statistical methodologies.
Rita Cantor, PhD Mathematical modeling of human disease traits.
Stephen Cederbaum, MD Identification, cloning, regulation and evolution of the two arginases, AI and AII, in man and experimental animals. The goal is to understand the basic biology and pathology of arginine metabolism and then find a treatment for arginase AI deficiency.
Esteban Dell Angelica, PhD Genetic Disorders of Organelle Biogenesis and Protein Trafficking.
Eleazar Eskin, PhD Bioinformatics, Genomics, Computational Methods for Analysis of Complex Traits.
Guoping Fan, PhD Molecular and cellular mechanisms underlying neuronal differentiation; and generation of mouse models for human diseases.
Jonathan Flint, PhD Understanding how genes influence behaviour, in particular how genetic variation contributes to disease susceptibility.
Brent Fogel, MD, PhD Basic and fundamental molecular mechanisms underlying human neurodevelopment and neurodegenerative disease.
Nelson Freimer, MD Genetic basis of complex traits, particularly neurobehavioral disorders including bipolar disorder, schizophrenia, depression, and Tourette Syndrome.
Michael Gandal, MD, PhD Genetic and genomic sequencing technologies to pinpoint the precise molecular mechanisms in human brain that contribute to neuropsychiatric disorders.
Richard Gatti, MD Current research focuses on the molecular genetics, diagnostics, radiobiology, and treatment of children with ataxia-telangiectasia, a progressive neurological disease of children.
Dan Geschwind, MD, PhD The Geschwind laboratory focuses on integrating basic neurobiology, genetics, and genomics with translational studies of human diseases.
Michael Gorin, MD, PhD Primarily devoted to research and clinical care of hereditary retinal disorders, especially age-related macular degeneration, retinal dystrophies and other medical retinal conditions.
Wayne Grody, MD, PhD Regulation of gene expression in the human arginase system and arginase deficiency; role of arginase in cancer cell proliferation; technical and ethical aspects of molecular genetic screening; development of novel DNA diagnostics.
Eran Halperin, PhD Develops statistical and cmputational methods for the analysis of human genetic and epigenetic varation in the context of complex human diseases.
Steve Horvath, PhD Allelic Association Studies and Microarray Data Analysis.
Deborah Krakow, MD Define prenatal ultrasound parameters in the osteochondrodysplasias, the molecular basis of musculoskeletal disorders, and the gene expression patterns in the skeleton.
Leonid Kruglyak, PhD Genetic Basis of Phenotypic Variation.
Kenneth Lange, PhD Formulation of statistical methods for analyzing the genetic basis of common diseases.
Jingyi Jessica Li, PhD Statistical methods in biology and genomics, Sparse linear modeling and Bioinformatics.
Kirk Lohmueller, PhD Population genetics and genomics.
Chongyuan Luo, PhD Dr. Luo is interested in developing and applying new genomic and genetic technologies to address long-standing questions in human diseases including the causal cell type(s) of diseases and the functions of non-coding genetic variants.
Aldons J. Lusis, PhD Genetics of complex diseases such as atheroschlerosis using inbred animal strains as models.
Julian A. Martinez-Agosto, MD, PhD Genetics of growth signaling pathways in stem cells, cancer and overgrowth syndromes.
Stanley Nelson, MD Technology development for the analysis of complex traits: development of microarrays to study gene expression and SNP scoring.
Linda McCabe, PhD Newborn screening is the focus of Dr. McCabe's research.
Roel Ophoff, PhD Genetics of neuropsychiatric traits.
Päivi Pajukanta, MD, PhD Genetics of cardiovascular diseases
Christina Palmer, PhD Centers on genetics of complex behaviors and the educational, psychological, and behavioral outcomes of genetic counseling and genetic testing.
Jeanette Papp, PhD Bioinformatic solutions for the management and analysis of all types of genetic data.
Bogdan Pasaniuc, PhD Statistical and computational methods for understanding genetic risk factors for common diseases, particular focus in the study of admixed populations.
Matteo Pellegrini, PhD Development of computational approaches to interpret genomic data.
Joseph Pisegna, MD Molecular pharmacology of hormones and receptors in the gastrointestinal tract, diagnosis and management of islet cell tumors of the pancreas.
Karen Reue, PhD Genes underlying disorders in lipid and glucose metabolism.
Jerome Rotter, MD Genetics of complex diseases: inflammatory bowel disease, atherosclerosis, diabetes.
Janet Sinsheimer, PhD Mathematical models of evolution and genetics.
Eric Sobel, PhD Statistical genetics methodologies for large pedigrees.
Sriram Sankararaman, PhD Novel methods to analyze large-scale genomic data to understand how genetic variation leads to phenotypic variation.
Marc Suchard, MD, PhD Mathematical and statistical phylogenetics, evolutionary medicine, computational biology, Bayesian methods.
Eric Vilain, MD, PhD Genetics of sex determination and development of the human reproductive system.
Yi Yin, PhD Understanding homologous recombination and resulting genome instability.
Stephen Young, MD During the past few years, we have worked on two general areas, the pathogenesis of hypertriglyceridemia and diseases of the nuclear lamina. Our laboratory works on molecules as they relate to human disease, and we make use of diverse techniques in molecular and cellular biology. When appropriate, we make use of genetically modified mice to investigate our research questions.
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