• Gryphon Login
  • MyCourses
  • UCLA Health
  • Contact Us
Cardiovascular

UCLA Cardiovascular Research Theme

Cardiovascular
  • Mission and Leadership
    • CV Theme Leadership
    • Unified Vision for UCLA Research Themes
  • Research Faculty
  • Research Programs
    • Vascular Biology
    • Cardiovascular Calcification
    • Cardiovascular Genomics and Systems Biology
    • Cardiac Repair, Regeneration, and Heart Failure
    • Atherosclerosis and Lipid biology
    • Arrhythymia, Sudden Cardiac Death, and Ion channel biology
    • Cardiac Development and Congenital Heart Disease
  • Clinical Investigations
    • Cardiovascular Research in Precision Health
    • Structural Cardiology
  • Seminars
    • CTSI Lecture Series
    • CV Theme Seminars
  • Core Services
    • CV Research Theme Small Animal Physiology Core
    • CV Research Theme Cardiac Muscle Cell Core
    • TCGB core
    • Molecular Shared Screening Resource
    • Confocal Microscopy and Imaging
  • Support Science
  • Gryphon Login
  • MyCourses
  • UCLA Health
  • Contact Us

UCLA Cardiovascular Research Theme

Yibin Wang, PhD

Yibin Wang, PhD 
Email: yibinwang@mednet.ucla.edu
Lab website →

Molecular Signaling and Systems Biology · Genetics and Genomics Regulation · Cardiometabolic Diseases Pathophysiology and Therapy

The long-term mission of Wang Lab is to understand how stress signaling leads to pathological changes in heart and metabolic system. Using systems genetic approaches and genomic tools, Wang Lab is conducting research in three major areas: 1). Investigating novel epigenetic regulators (lncRNAs and RNA-binding proteins) in stress-induced pathological remodeling and cellular responses in heart, fat and liver. 2). Discovering novel regulatory mechanisms in Branched-Chain Amino Acids metabolism in cellular nutrient signaling and pathophysiology. 3). Identify novel mechanism, therapeutic targets and developing novel therapies through systems genetics for heart failure and metabolic disorders.

Publications

  • Yokota T, Li J, Huang J, Xiong Z, Zhang Q, Chan T, Ding Y, Rau C, Sung K, Ren S, Kulkarni R, Hsiai T, Xiao X, Touma M, Minamisawa S, Wang Y. p38 Mitogen-activated protein kinase regulates chamber-specific perinatal growth in heart. J Clin Invest. 2020 Aug 31;. doi: 10.1172/JCI135859. [Epub ahead of print] PubMed PMID: 32573492.
  • Wang Z, Zhang XJ, Ji YX, Zhang P, Deng KQ, Gong J, Ren S, Wang X, Chen I, Wang H, Gao C, Yokota T, Ang YS, Li S, Cass A, Vondriska TM, Li G, Deb A, Srivastava D, Yang HT, Xiao X, Li H, Wang Y. The long noncoding RNA Chaer defines an epigenetic checkpoint in cardiac hypertrophy. Nat Med. 2016 Oct;22(10):1131-1139. doi: 10.1038/nm.4179. Epub 2016 Sep 12. PubMed PMID: 27618650; PubMed Central PMCID: PMC5053883.
  • Sun H, Olson KC, Gao C, Prosdocimo DA, Zhou M, Wang Z, Jeyaraj D, Youn JY, Ren S, Liu Y, Rau CD, Shah S, Ilkayeva O, Gui WJ, William NS, Wynn RM, Newgard CB, Cai H, Xiao X, Chuang DT, Schulze PC, Lynch C, Jain MK, Wang Y. Catabolic Defect of Branched-Chain Amino Acids Promotes Heart Failure. Circulation. 2016 May 24;133(21):2038-49. doi: 10.1161/CIRCULATIONAHA.115.020226. Epub 2016 Apr 8. PubMed PMID: 27059949; PubMed Central PMCID: PMC4879058.

Full NIH Bibliography

Like Us on Facebook Follow Us on Twitter Subscribe to Our Videos on YouTube Follow us on Instagram Connect with Us on LinkedIn Follow us on Pinterest Follow us on Flickr Follow us on Sharecare
Top U.S. Medical Schools in Primary Care
  • Giving
  • Contact Us
  • Diversity
  • Emergency
  • Maps & Directions
  • Publications
  • Directory
  • Report Misconduct
  • Volunteer
  • Biomed Library
  • Newsroom
  • Smoke-Free
  • Sitemap
  • Terms of Use
  • Report Broken Links
Top U.S. Medical Schools in Research
Like Us on Facebook Follow Us on Twitter Subscribe to Our Videos on YouTube Follow us on Instagram Connect with Us on LinkedIn Follow us on Pinterest Follow us on Flickr Follow us on Sharecare