Apply for CIRM's Clinical Trial (CLIN2) Research Funding Opportunity

The mission of the California Institute for Regenerative Medicine (CIRM) is to accelerate world class science to deliver transformative regenerative medicine treatments in an equitable manner to a diverse California and world.

CIRM’s CLIN2 program will support the completion of phase 1, 2, or 3 clinical trials— including pivotal trials— for regenerative medicine therapies that address significant unmet medical needs and have the potential to provide transformative benefits to patients, their families, and the healthcare system. Through this program, CIRM creates funding opportunities for regenerative medicine clinical research that otherwise do not exist or are of limited scope. CIRM will devote internal resources and leverage a network of world-class subject matter experts to help ensure that funded projects have a comprehensive clinical development strategy aimed at obtaining marketing approval with a well-developed plan for ensuring access and affordability.

Download the CLIN2 Program Announcement (PA) for more information on award eligibility, review criteria, and the application process.

Download Program Announcement PDF

Expected Outcomes

The expected outcome of a CLIN2 award is completion of a single interventional clinical trial. 

To be eligible:

California or non-California-based for-profit or non-profit organizations may apply

Award Amount & Duration

The award amount ranges from $8 million to $15 million and is dependent on the stage of the clinical trial and the for-profit versus non-profit status of the applicant organization. Projects may have a maximum planned duration of four years.