His research focuses on cell signaling systems and network dynamics that determine biological specificity. He has studied how the epigenome may be altered by inducible signaling systems to alter the cellular steady state. In his lab computational modeling and bioinformatic analysis is iterated with experimental work in animals at single-molecule to genome-wide scales. He is the director of the Institute for Quantitative and Computational Biosciences (QCBio). He is deeply committed to undergraduate and graduate research training. He has been the PI of two T32 Training Grants. Since coming to UCLA, 20 graduate students have earned PhD’s in his laboratory. He is chair of the UCLA Committee for Diversity and Equity (CDE) and the Chancellor’s Council on Diversity. He launched the UCLA Bruins-In-Genomics (BIG) Summer Undergraduate Research program.
Research interests include neurogenetics and studying genetic mutations that are related to neurodegenerative diseases.
Department: Microbiology, Immunology and Molecular Genetics