Understanding the brain to fight brain cancer

Glioblastoma is one of the most devastating brain tumors we know of, and one reason it is so hard to treat is that it doesn't play by normal rules. 

A new review from Aparna Bhaduri's lab at David Geffen School of Medicine at UCLA reveals why: GBM tumor cells behave like cells from a developing brain, proliferating and differentiating, but without the normal controls. 

By studying the progenitor cells that build the human cortex, Bhaduri's lab is finding unexpected parallels that could point toward new therapeutic strategies. Understanding the brain to fight brain cancer. This is what neuroscience at the intersection of cancer biology looks like. 

Read the entire paper: Progenitor Types in the Human Cortex in Normal Development and Glioblastoma